1. Zhang, X. J.; Li, X.; Sun, H. P.; Wang, X. J.; Zhao, L.; Gao, Y.; Liu, X.; Zhang, S.; Wang, Y.; Yang, Y.; Zeng, S.; Guo, Q.; You, Q. Garcinia xanthones as orally active antitumor agents. J Med. Chem. 2013, 56, 276-92.
2. Jian-Min Jia, Xiao-Li Xu, Fang Liu, Xiao-Ke Guo, Ming-Ye Zhang, Meng-Chen Lu, Li-Li Xu, Jin-Lian, Wei, Jia Zhu, Sheng-Lie Zhang, Sheng-Miao Zhang, Hao-Peng Sun and Qi-Dong You. Identification, Design and Bio-evaluation of Novel Hsp90 Inhibitor by Ligand-based Virtual Screening. Plos One, 2013, accept.
3. Jing-Jie Huang, Xiao-Wen Wu, Jian-Min Jia, Xiao-Ke Guo, Xin Xue, Zheng-Yu Jiang, Sheng-Lie Zhang, Xiao-Jin Zhang, Hao-Peng Sun, and Qi-Dong You. Novel IKKβ inhibitors discovery based on the co-crystal structure by using binding-conformation-based and ligand-based method. Eur. J Med. Chem. 2013. Accept
4. You Zhou, Xiao-Li Xu, Yuan Sun, Hua-PingWang, Hao-Peng Sunand Qi-Dong You. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives. 2013 accept.)
5. Jie-Wei Jiang, Ying-Sun, Ying-Nie, Hui-Jing, Zhi, Xiao-Jin, Zhang, Xiang Li, Hao-Peng Sun, and Qi-Dong You. Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives. 2013 accept.
6. Yan Chen, Hui Hui, Hao Yang, Kai Zhao, Yansu Qin, Cong Gu, Xiaotang Wang, Na Lu, and Qinglong Guo. Wogonoside induces cell cycle arrest and differentiation by affecting expression and subcellular localization of PLSCR1 in AML cells. Blood. (Accepted,IF10.558)
7. Libin Wei, Yuxin Zhou, Qinsheng Dai, Chen Qiao, Li Zhao, Hui Hui, Na Lu, Qinglong Guo. Oroxylin A induces dissociation of hexokinase II from the mitochondria and inhibits glycolysis by SIRT3 mediated deacetylation of cyclophilin D in breast carcinoma. Cell Death & Disease (Accepted, IF5.333)
8. Libin Wei, Qinsheng Dai, Yuxin Zhou, Meijuan Zou, Zhiyu Li, Na Lu*, Qinglong Guo*. Oroxylin A sensitizes non-small cell lung cancer cells to anoikis via glucose-deprivation-like mechanisms: c-Src and hexokinase II. Biochimica et Biophysica Acta (BBA)-General Subjects. (Accepted, IF5.00)
9. Yajing Sun, Meijuan Zou, Chen Hu, Yansu Qin, Xiuming Song, Na Lu, Qing-Long Guo*. Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway. Food and Chemical Toxicology. 51(2013):53-60(IF2.999)
11. Min Xu, Na Lu, Haiwei Zhang, Qinsheng Dai, Libin Wei, Zhiyu Li, Qidong You and Qinglong Guo*. Wogonin induced cytotoxicity in human hepatocellular carcinoma cells by activation of unfolded protein response and inactivation of AKT. Hepatology Research. (IF2.199)
12. Litao Zhu, Li Zhao, Hu Wang, Yu Wang, Di Pan, Jing Yao, Zhiyu Li, Guanzhong Wu, Qinglong Guo*.Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest. Toxicology Letters. (IF3.230)
13. Fei Wang, Xiuming Song, Mi Zhou, Libin Wei, Qinsheng Dai, Zhiyu Li, Na Lu, Qinglong Guo*. Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. Toxicology. (IF3.681)
14. Cheng X, Liu F, Yan T, Zhou X, Wu L, et al. (2012) Metabolic Profile, Enzyme Kinetics, and Reaction Phenotyping of beta-Lapachone Metabolism in Human Liver and Intestine in Vitro. Mol Pharm. 2012 Nov 16. [Epub ahead of print]
15. Hao K, Qi Q, Hao H, Wang G, Chen Y, et al. (2013) The pharmacokinetic-pharmacodynamic model of azithromycin for lipopolysaccharide-induced depressive-like behavior in mice. PLoS One 8: e54981.
16. Zha W, Wang G, Xu W, Liu X, Wang Y, et al. (2013) Inhibition of P-Glycoprotein by HIV Protease Inhibitors Increases Intracellular Accumulation of Berberine in Murine and Human Macrophages. PLoS One 8: e54349.
17. Zheng T, Liu L, Aa J, Wang G, Cao B, et al. (2013) Metabolic phenotype of rats exposed to heroin and potential markers of heroin abuse. Drug Alcohol Depend 127: 177-186.
18. Zhou X, Xie Y, Qi Q, Cheng X, Liu F, et al. (2013) Disturbance of Hepatic and Intestinal UDP-Glucuronosyltransferase in Rats with Trinitrobenzene Sulfonic Acid-Induced Colitis. Drug Metab Pharmacokinet. 2013 Jan 1. [Epub ahead of print]
19. Cao B, Li M, Zha W, Zhao Q, Gu R, et al. (2013) Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells. Metabolomics, Accepted on 2nd, March, 2013.
20. Yang X, Zhang F, Wang Y, Cai M, Wang Q, Guo, QL, Li ZY, Hu R*. Oroxylin A inhibits colitis-associated carcinogenesis via modulating the IL-6/STAT3 signaling pathway. (Accepted for publication in Inflammatory Bowel Diseases)
21. Sun, H. P.; Chen, F. H.; Wang, X. J.; Liu, Z. L.; Yang, Q.; Zhang, X. J.; Zhu, J.; Qiang, L.; Guo, Q. L.; You, Q. D. Studies on gambogic acid (IV): Exploring structure-activity relationship with I kappa B kinase-beta (IKK beta). Eur. J Med. Chem. 2012, 51, 110-123.
22. Sun, H. P.; Liu, Z. L.; Xue, X.; Gao, Y.; Zhang, L.; Wang, J. X.; Guo, Q. L.; You, Q. D. Studies on Chemical Structure Modification and Structure-Activity Relationship of Derivatives of Gambogic Acid at C(39). Chem. Biodivers. 2012, 9, 1579-1590.
23. Zhang, X. J.; Li, X.; Yang, Y. R.; Sun, H. P.*; Gao, Y.; Zhang, L.; Wang, J. X.; Guo, Q. L.; You, Q. D. Studies on Chemical-Structure Modification and Structure?Activity Relationship of Gambogic Acid Derivatives at Carbon(34). Chem Biodivers. 2012, 9, 2295-2308.
24. Guo, X. K.; Sun, H. P.; Shen, S.; Sun,Y.; Xie, F. L. Tao, L.; Guo, Q. L.; Jiang, C.; You, Q. D. Synthesis and Evaluation of Gambogic Acid Derivatives as Antitumor Agents Part III. Chem Biodivers. Accept.
25. Tan, Y. Y.; Chen, Y. D.; You, Q. D.; Sun, H. P.; Li, M. H. Predicting the potency of hERG K+ channel inhibition by combining 3D-QSAR pharmacophore and 2D-QSAR models. J Mol. Model. 2012, 18, 1023-1036.
26. Huang, K.; Wu, X. W.; Jiang, Z. Y.; Sun, H. P.*; You, Q. D. Novel Dual-Site-Binding Neuraminidase Inhibitor from Virtual Screening by Pharmacophore and Molecular Dynamics Methods. Chinese J Chem. 2012, 30, 1735-1740.
27. Li, X.; Zhang, X. J.; Sun, H. P.*; Zhang, L.; Gao, Y.; Wang, J. X.; Guo, Q. L.; You, Q. D. Synthesis and Anti-tumor Evaluation of Novel C-37 Modified Derivatives of Gambogic Acid. Chinese J Chem. 2012, 30, 1083-1091.
28. Yang X, Zhang F, Wang Y, Cai M, Wang Q, Guo, QL, Li ZY, Hu R*. Oroxylin A inhibits colitis-associated carcinogenesis via modulating the IL-6/STAT3 signaling pathway. (Accepted for publication in Inflammatory Bowel Diseases)
29. Yao J, Hu R (co-contributing author), Sun J, Lin B, Zhao L, Sha Y, You QD, Yan T, Guo QL. Oroxylin A prevents inflammation-related tumor through down-regulation of inflammatory gene expression by inhibiting NF-κB signaling. Mol Carcinog. 2012 Sep 4. [Epub ahead of print]
30. Hu R, Chen N, Yao J, Zhao Q, Zhang F, Li ZY, You QD, Guo QL. The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors. Anticancer Drugs. 2012 Jul;23(6):651-8.
31. Liu F, Yu G, Wang G, Liu H, Wu X, et al. (2012) An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancer. PLoS One 7: e42138.
32. Liu L, Cao B, Aa J, Zheng T, Shi J, et al. (2012) Prediction of the pharmacokinetic parameters of triptolide in rats based on endogenous molecules in pre-dose baseline serum. PLoS One 7: e43389.
33. Zha W, Zha BS, Zhou F, Zhou H, Wang G (2012) The cellular pharmacokinetics of HIV protease inhibitors: current knowledge and future perspectives. Curr Drug Metab 13: 1174-1183.
34. Wei Fu , Qinglong Guo , Zhiyu Li* et al. Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives Bioorg. Med. Chem. Lett. 22 1118–1121 2012
35. Na Lu, Zhiyu Li*, Qinglong Guo* et al. VI-16, a newly synthesized flavonoid, induces apoptosis through the mitochondrial pathway in human hepatoma cells ONCOLOGY REPORTS 27: 873-879, 2012
36. Xiaoyun Zhang, Zhiyu Li*, Qinglong Guo* ,et al. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors Bioorg. Med. Chem. Lett. 22 1276–1281 2012
37. Yansu Qin, Zhiyu Li, Na Lu*, Qinglong Guo*, et al. III-10, a newly synthesized flavonoid, induced differentiation of human U937 leukemia cells via PKCδ activation European Journal of Pharmaceutical Sciences 45(5): 648-56 2012
38. Su, Y. X.; Deng, Y. H.; Ma, T. T.; Li, Y. Y.; Sun, L. P. “On Water” direct Pd-catalysed C-H arylation of thiazolo[5,4-d]pyrimidine derivatives. Green Chem. 2012, 14, 1979–1481.
39. Xu, D.; Sun, L. P.; You, Q. D. Facile synthesis of 2, 5, 7-trisubstituted oxazolo[5,4-d]pyrimidines via copper-catalyzed intramolecular C-O bond formation. Tetrahedron. 2012, 68, 4248–4251.
40. Su, Y. X.; Sun, L. P. Recent progress towards transition-metal-catalyzed direct arylation of heteroarenes. Mini. Rev. Org. Chem. 2012, 9, 87–117.
41. Lei Shi*, Lu Wang, Zhi Wang, Hai-Liang Zhu, Qiao Song. Synthesis of novel cinnamanilides as potential immunosuppressive agents. Eur. J. Med. Chem., 2012, 47, 585-593.
42. Bin Hu, Qiao Song, Yungen Xu*. Scale-up Synthesis of Antidepressant Drug Vilazodone. Org Process Res Dev. 2012, 16, 1552-1557.
43. Xiao-Zhi Yang, Wen-Hui Yang, Yun-Gen Xu*, Xiao-Juan Diao, Guang-Wei He, Guo-Qing Gong. Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activity. Eur J Med Chem, 2012, 57, 21-28.
44. Qihua Zhu, Xuyan Wang, Yungen Xu*. Palladium-Catalyzed Tandem Reactions of β-(2-Bromophenyl)-α,β- Unsaturated Carbonyl Compounds with 2-Hydroxyphenylboronic Acid: A New Route to Benzo[c]chromenes. Eur J Org Chem, 2012, 6, 1112-1114.
45. Zongjie Gan, Bin Hu, Qiao Song, Yungen Xu*. Convenient Chlorination of Some Special Aromatic Compounds using N-Chlorosuccinimide. Synthesis-Stuttgart, 2012, 44, 1074-1078.
46. Xin MH, Gao Y, Xiang H*, Chen D, He Y, You QD. A General and Facile Synthesis of Novel Polysubstituted Quinazolin-4(3H)-ones. J Heterocycl Chem, 2013, 50, 169-174.
47. Chen D, Yang K, Xiang H*, Jiang S. New ligands for copper-catalyzed C–N coupling reactions with aryl halides, Tetra Lett, 2012, 53, 7121-7124.